Intestinal perforation due to paradoxical reaction during treatment for miliary tuberculosis

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Intestinal perforation due to paradoxical reaction during treatment for miliary tuberculosis

A 61-year-old man was being treated for poor nutritional status. He had been on weekly methotrexate 6 mg and daily tacrolimus 1 mg and prednisolone 18 mg for 8 years due to dermatomyositis. On further workup, he was initially detected to have ileocecal ulcer with subsequent development of diffuse miliary shadows on chest radiograph. He was diagnosed as having ileocecal with miliary tuberculosis...

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Tuberculosis paradoxical reaction.

T is endemic in this part of the world. We frequently encounter patients with both pulmonary and extrapulmonary tuberculosis regardless of whether they are infected with human immunodeficiency virus (HIV) or not. It is not uncommon for physicians to see clinical or radiological, or both, worsening of the disease while their patient is on anti-tuberculous treatment, the so-called paradoxical rea...

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Tumor necrosis factor (TNF)-alpha inhibitors play an important role in the treatment of immun-mediated diseases such as Crohn's disease. But they also have been related to increased risk for disseminated Mycobacterium tuberculosis infections and paradoxical response to antimycobacterial treatment. Here we report a disseminated tuberculosis case and a paradoxical response to treatment after rece...

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[Bowel perforation secondary to intestinal tuberculosis].

Tuberculosis (TB) continues to be a major health problem worldwide and one of the illness that should be kept in mind currently due to its varying clinical symptoms. Its incidence is increasing in developed countries, where most cases of multifocal TB are reported among immigrants from high endemic areas and in immunodepressed subjects (1). WHO estimates that there were 9,2 million new cases of...

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Spontaneous Splenic Rupture as a Paradoxical Reaction during Treatment for Splenic Tuberculosis

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ژورنال

عنوان ژورنال: Respirology Case Reports

سال: 2016

ISSN: 2051-3380,2051-3380

DOI: 10.1002/rcr2.196